- Yoko Ono
- Zooey Deschanel
- Chuck Yeager
- Yogi Bera
- Yanni
- Zane Gray
- Yesica Toscanini
- Weird Al Yankovich
- Carlos Zambrano
- Yao Ming
- Zachery Ty Bryan
- Yasmine Bleeth
- Yoshi Tatsu
- Malcom X
- Cy Young
- James Zahara
- Sgt. York
- Renee Zellweger
- Catherine Zeta-Jones
- Rob Zombie
- Daphne Zuniga
- Tina Yothers
- Fuzzy Zoeller
- Ma Ying-jeou
- Yul Brynner
- Vern Troyer