- April 16, 1178BC – A solar eclipse may have marked the return of Odysseus, legendary King of Ithaca, to his kingdom after the Trojan War
- February 16, 374 – 9th recorded perihelion passage of Halley’s Comet
- February 16, 600 – Pope Gregory the Great decrees saying “God bless You” is the correct response to a sneeze
- November 16, 1380 – French King Charles VI declares no taxes for ever
- October 16, 1492 – Columbus and his fleet anchor at “Fernandina” (Long Island, Bahamas)
- September 16, 1795 – British capture Capetown, South Africa, from the Dutch
- March 16, 1830 – Slowest day ever recorded on NYSE (31 shares traded)
- June 16, 1858 – Abraham Lincoln says “A house divided against itself cannot stand”, while accepting nomination to Senate
- July 16, 1861 – Battle of Bull Run (First major battle in Civil War)
- January 16, 1870 – Virginia becomes 8th state readmitted to US after Civil War
- May 16, 1919 – Birth of Liberace
- December 16, 1929 – Chicago Blackhawks first game at Chicago Stadium (Defeated Pittsburgh Pirates 3-1)
- January 16, 1973 – NBC airs final episode of Bonanza
- November 16, 1981 – Luke & Laura marry on General Hospital
- May 16, 2013 – Human stem cells are successfully cloned
- March 16, 2017 – Donald Trump’s second travel ban is blocked by two federal court judges